KMID : 1040420210250020117
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Childhood Kidney Diseases 2021 Volume.25 No. 2 p.117 ~ p.121
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Extraskeletal Calcifications in Children with Maintenance Peritoneal Dialysis
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Oh Eun-Hye
Min Jee-Su Lim Seon-Hee Kim Ji-Hyun Ha Il-Soo Kang Hee-Gyung Ahn Yo-Han
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Abstract
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Chronic kidney disease (CKD)-mineral and bone disorder (CKD-MBD) is a common complication of CKD, often accompanied by extra-skeletal calcification in adult patients. As increased vascular calcification is predicted to increase cardiovascular mortality and morbidity, the revised Kidney Disease: Improving Global Outcomes guidelines recommend avoiding calcium-containing phosphate chelators. However, extra-skeletal calcification is less commonly noticed in pediatric patients. Here, we report our experience of such a complication in pediatric patients receiving maintenance peritoneal dialysis. Extra-skeletal calcification was noticed at the corneas, pelvic cavity, and soft tissues of the lower leg in 4 out of 32 patients on maintenance peritoneal dialysis. These patients experienced the aggravation of extra-skeletal calcifications during peritoneal dialysis, and 2 of them underwent excisional operations. It is required to monitor extra-skeletal calcifications in children on kidney replacement therapy.
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KEYWORD
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Chronic kidney disease-mineral and bone disorder, Pathologic calcification, Peritoneal dialysis
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